The 49 XXXXX syndrome (also called as Penta X or pentasomy X) is a chromosomal condition that affects females. In a normal setup, females have only two X chromosomes and anything beyond this is abnormal. In the case of Penta X syndrome, there are an additional three X chromosomes which now totals five. The three additional X chromosomes are the ones that cause multiple problems. These extra X chromosomes are formed together with the two healthy chromosomes inside the nucleus of the human body cells.
There are no known environmental factors or even age factors that cause the Penta X syndrome. This condition is actually a result of some errors during reproductive cell division in one of the two parents. All other information pertaining to it is limited as there are only a few studies about this chromosomal abnormality.